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Results for "

terminal alkyne

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Bacterial (2) Biochemical Assay Reagents (2) Deubiquitinase (1) Epigenetic Reader Domain (1) Fluorescent Dye (9) Liposome (1) PROTAC Linkers (2)
By Research Areas:	Cancer (5) Infection (2) Metabolic Disease (1)
Click Chemistry:	Labeling and Fluorescence Imaging (2) PROTAC Synthesis (2) Azide (5) Alkynes (8)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Click Chemistry

Targets Recommended: JNK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1455

Falcarinol Panaxynol; Carotatoxin
Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis . Falcarinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-132273

Alkyne Phosphoramidite, 5'-terminal

Biochemical Assay Reagents Others

Alkyne Phosphoramidite, 5'-terminal (Compound 2) can be used for synthesis of oligo-nucleotides.

**Alkyne Phosphoramidite, 5'-terminal**	Biochemical Assay Reagents	Others
Alkyne Phosphoramidite, 5'-terminal (Compound 2) can be used for synthesis of oligo-nucleotides.

HY-D1664

BDP 558/568 alkyne	Fluorescent Dye	Others
BDP 558/568 alkyne is a borondipyrromethene dye. BDP 558/568 alkyne possesses high quantum yield. BDP 558/568 alkyne is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=558 nm, λ_em=568 nm) .

HY-151665

Alkyne-PEG2-iodide

ADC Linker Others

Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

Alkyne-PEG2-iodide	ADC Linker	Others
Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

HY-D1333

BDP 630/650 alkyne	Fluorescent Dye	Others
DP 630/650 alkyne is a red fluorescent dye with λ_excitation of 630 nM and λ_emission of 650 nM. The terminal alkyne group can be conjugated with various azides by copper catalyzed Click chemistry. BDP 630/650 alkyne can be used for fluorescence polarization assays .

HY-151705

Alkyne Cholesterol	Liposome	Metabolic Disease
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-147097A

EDA-DA TFA	Bacterial	Infection
EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-112789

(+)-JQ1 PA 1 Publications Verification	Epigenetic Reader Domain	Cancer
(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC₅₀ of 10.4 nM. (+)-JQ1 PA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1320

Cyanine5 azide chloride	Fluorescent Dye	Others
Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λ_ex=646 nm, λ_em=662 nm) .

HY-D1321

Cy 5 amine Cyanine5 amine(hydrochloride)	Fluorescent Dye	Others
Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λ_ex=646 nm, λ_em=662 nm) .

HY-129832

Biotin-azide 2 Publications Verification N-(3-Azidopropyl)biotinamide	Biochemical Assay Reagents	Others
Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry . Biotin-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-147097

EDA-DA	Bacterial	Infection
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1721

Fluorescein-12-dATP	Fluorescent Dye	Others
Fluorescein-12-dATP is a fluorescent dye acting as the detection probe. Fluorescein-12-dATP can be used to label the thrombin-binding aptamers by catalytic polymerization of TdT (terminal deoxynucleotidyl transferase) . Fluorescein-12-dATP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1649

BDP R6G amine	Fluorescent Dye	Others
BDP R6G amine is a fluorophore based on borondipyrromethene scaffold. BDP R6G amine is a BDP linker containing an amine group. BDP R6G amine is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=530 nm, λ_em=548 nm).

HY-151774

TAMRA hydrazide (6-isomer)	Fluorescent Dye	Others
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .

HY-130598

N-(Azido-PEG3)-N-Boc-PEG4-acid	PROTAC Linkers	Cancer
N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs N-(Azido-PEG3)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-D2161

AF 594 azide	Fluorescent Dye	Others
AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne).

HY-D2161A

AF 594 azide triethylamine	Fluorescent Dye	Others
AF 594 azide (triethylamine) is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide (triethylamine) forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne).

HY-130312

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester	PROTAC Linkers	Cancer
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-D1726

8RK59	Deubiquitinase	Cancer
8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC₅₀ close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .

Cat. No.	Product Name	Type

HY-D1320

Cyanine5 azide chloride	Dyes
Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λ_ex=646 nm, λ_em=662 nm) .

HY-D1664

BDP 558/568 alkyne	Fluorescent Dyes/Probes
BDP 558/568 alkyne is a borondipyrromethene dye. BDP 558/568 alkyne possesses high quantum yield. BDP 558/568 alkyne is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=558 nm, λ_em=568 nm) .

HY-D1321

Cy 5 amine Cyanine5 amine(hydrochloride)	Dyes
Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λ_ex=646 nm, λ_em=662 nm) .

HY-D1649

BDP R6G amine	Fluorescent Dyes/Probes
BDP R6G amine is a fluorophore based on borondipyrromethene scaffold. BDP R6G amine is a BDP linker containing an amine group. BDP R6G amine is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=530 nm, λ_em=548 nm).

HY-151774

TAMRA hydrazide (6-isomer)	Fluorescent Dyes/Probes
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .

HY-D2161

AF 594 azide	Fluorescent Dyes/Probes
AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne).

HY-D2161A

AF 594 azide triethylamine	Fluorescent Dyes/Probes
AF 594 azide (triethylamine) is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide (triethylamine) forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne).

HY-D1726

8RK59	Fluorescent Dyes/Probes
8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC₅₀ close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .

Alkyne Cholesterol	Drug Delivery
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

Biotin-azide 2 Publications Verification N-(3-Azidopropyl)biotinamide	Biochemical Assay Reagents
Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry . Biotin-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-151705

Alkyne Cholesterol		Labeling and Fluorescence Imaging Alkynes
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-112789

(+)-JQ1 PA 1 Publications Verification		Alkynes
(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC₅₀ of 10.4 nM. (+)-JQ1 PA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151665

Alkyne-PEG2-iodide

Alkynes

Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

Alkyne-PEG2-iodide		Alkynes
Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

HY-147097A

EDA-DA TFA		Alkynes
EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-115715A

EN219-alkyne		Alkynes
EN219-alkyne is an alkyne-functionalized EN219 probe. EN219 (HY-P0287A) is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC₅₀ of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination . EN219-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1320

Cyanine5 azide chloride		Azide
Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λ_ex=646 nm, λ_em=662 nm) .

HY-127112

Oleic acid alkyne		Alkynes
Oleic acid alkyne is oleic acid with an acetylene group. The terminal alkyne group can be used for click chemical ligation reactions. Oleic acid can be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH). Through click chemistry reactions, fluorescent or biotin-labeled oleic acid can be introduced to analyze its metabolism and biological activity.

HY-129832

Biotin-azide 2 Publications Verification N-(3-Azidopropyl)biotinamide		Azide Labeling and Fluorescence Imaging
Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry . Biotin-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-147097

EDA-DA		Alkynes
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130598

N-(Azido-PEG3)-N-Boc-PEG4-acid		PROTAC Synthesis Azide
N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs N-(Azido-PEG3)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-D2161

AF 594 azide		Azide
AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne).

HY-130312

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester		PROTAC Synthesis Azide
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-129084

Propargylcholine bromide		Alkynes
Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells . Propargylcholine (bromide) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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